Lipids and Lipid Derivatives
Apexbio Technology LLC Desvenlafaxine Succinate 386750-22-7 25mg
Desvenlafaxine Succinate (CAS 386750-22-7) is a small molecule inhibitor that targets both the serotonin (5-HT) and norepinephrine (NE) transporters It acts by blocking the reuptake of these neurotransmitters thereby modulating synaptic concentrations In in vitro assays Desvenlafaxine Succinate demonstrates a high affinity for the serotonin transporter (K sub i /sub 40 2 nM) and a lower affinity for the norepinephrine transporter (K sub i /sub 558 4 nM) This compound is utilized in biomedical research to investigate the pharmacological mechanisms underlying monoaminergic neurotransmission and to study potential therapeutic strategies for neuropsychiatric conditions involving serotonergic and noradrenergic pathways
Medchemexpress LLC Cortodoxone-d2 | 1271728-08-5 | 99.0% | C21H28D2O4 | 1 MG
Cortodoxone-d2 is a deuterium labeled glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone). It is suitable for use as a tracer or an internal standard for quantitative analysis in various analytical techniques.
- Can be used as a tracer.
- Acts as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes as tracers for quantitation in drug development.
- Deuteration offers potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Ethyl palmitate | 628-97-7 | 1000 G
Ethyl palmitate is a CHIKV virus inhibitor with an EC50 value of 0.0068 μM. It demonstrates anti-inflammatory activity by reducing levels of TNF-α, IL-6, and NF-κB in endotoxemic rats.
- Inhibits the expression and viral activity of CHIKV virus E2 protein
- Decreases plasma levels of TNF-α and IL-6
- Reduces NF-κB expression in liver and lung tissues
- Ameliorates histopathological changes caused by LPS in a rat model
- Inhibits phagocytic function of the reticuloendothelial system (RES)
Medchemexpress LLC Glepaglutide acetate | 99.5% | 4376.06 | 25 MG
Glepaglutide acetate is a long-acting GLP-2 analogue and a potent GLP-2R agonist. It reduces faecal output and increases intestinal absorption. Glepaglutide acetate alleviates small intestinal inflammation.
- Can be used in research of inflammatory bowel disease (IBD)
- Can be used in research of Crohn's disease
- Reduces faecal output
- Increases intestinal absorption
- Alleviates small intestinal inflammation
Medchemexpress LLC Tat-cbd3a6k (acetate) | 99.8% | 3249.83 (free base) | 5 MG
This modified peptide reduces T- and R-type voltage-dependent calcium currents in dorsal root ganglion (DRG) neurons. It demonstrates anti-nociceptive effects in a model of AIDS-induced peripheral neuropathy. This action is achieved by preventing enhancement of T- and R-type calcium channel function.
- Reduces T- and R-type voltage-dependent calcium currents.
- Shows anti-nociceptive effects.
- Acts by preventing enhancement of calcium channel function.
Medchemexpress LLC Isocitric acid (Standard) | 320-77-4 | 99.91% | 192.12 | 100 MG
Isocitric acid (Standard) is the analytical standard of Isocitric acid (HY-113228). This product is intended for research and analytical applications. It is an endogenous metabolite present in saliva and cellular cytoplasm that can be used for the research of Alzheimer's Disease, Lewy Body Dementia, and Anoxia. The compound is the grade of analytical standard, which is the reference standard supplied assay.
- Analytical standard for isocitric acid.
- Intended for research and analytical applications.
- Endogenous metabolite present in saliva and cellular cytoplasm.
- Can be used for the research of Alzheimer's disease, Lewy body dementia and anoxia.
- Commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Medchemexpress LLC Cetrorelix Acetate | 145672-81-7 | 99.9% | 1491.09 | 1 MG
Cetrorelix Acetate is a potent gonadotropin-releasing hormone (GnRH) receptor antagonist that inhibits the growth of the ES-2 cell line. It exhibits antiproliferative effects comparable to GnRH-I agonists. This product has a high purity of 99.9% and is supplied as a white to off-white solid. It requires specific storage conditions to maintain its stability, with powder stable for up to 2 years at -80°C and solutions for up to 6 months at -80°C.
- Potent GnRH receptor antagonist
- Inhibits ES-2 cell line growth
- Comparable antiproliferative effects to GnRH-I agonists
- High purity
- Stable under specific storage conditions
Medchemexpress LLC Ursolic acid acetate | 7372-30-7 | 1 MG
Ursolic acid acetate (Acetylursolic acid) is a triterpenoid compound and an inhibitor of *Plasmodium falciparum* heat shock protein 90 (PfHsp90) with a KD of 8.16 μM. It is cytotoxic to KB cells, with an IC50 value of 8.4 μM. Ursolic acid acetate can be used in tumor and antimalarial research.
- Triterpenoid compound
- Inhibitor of Plasmodium falciparum heat shock protein 90 (PfHsp90) (KD = 8.16 μM)
- Cytotoxic to KB cells (IC50 = 8.4 μM)
- Potential for use in tumor and antimalarial research
- Can reduce the ATPase activity of PfHsp90 in a dose-dependent manner (1-5 mM; 4.5 h)
- Has an IC50 of 24.93 μM against the P. falciparum FcB1 strain
Medchemexpress LLC Ethyl palmitate | 628-97-7 | 50 MG
Ethyl palmitate is an analytical standard and a fatty acid ethyl ester (FAEE). It is intended for research and analytical applications. This compound shows a marked preference for the synthesis of ethyl palmitate and ethyl oleate over other FAEEs in human subjects after ethanol consumption. Ethyl palmitate is also used as a hair- and skin-conditioning agent.
- Analytical standard for research and analytical applications
- Fatty acid ethyl ester (FAEE)
- Used as a hair- and skin-conditioning agent
- Commonly employed in qualitative, quantitative, and methodological research experiments including HPLC, GC, and MS
Medchemexpress LLC L-Glutamic acid, polymer with L-alanine, L-lysine and L-tyrosine, acetate (salt) | 147245-92-9 | 98.0% | 25 MG
L-Glutamic acid, polymer with L-alanine, L-lysine and L-tyrosine, acetate (salt) | 147245-92-9 | 98.0% | 25 MG
Medchemexpress LLC Icatibant acetate (HOE 140 acetate) | 138614-30-9 | 99.9% | 1364.57 | 25 MG
Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively.
- Potent and specific peptide antagonist of bradykinin B2 receptor.
- IC50 and Ki of 1.07 nM and 0.798 nM respectively for bradykinin B2 receptor.
- For research use only.
Medchemexpress LLC Nonanoic acid | 112-05-0 | 1 ML
Nonanoic acid, also known as Pelargonic acid, is a naturally-occurring saturated fatty acid with nine carbon atoms. It is a research-use-only product known for its role in reducing bacterial translocation, enhancing antibacterial activity, and increasing the secretion of porcine β-defensins 1 and 2. It functions by upregulating endogenous host defense peptides to improve intestinal epithelial immunological barrier function through histone deacetylase inhibition.
- Naturally-occurring saturated fatty acid
- Reduces bacterial translocation
- Enhances antibacterial activity
- Increases secretion of porcine β-defensins
- Upregulates endogenous host defense peptides
- Enhances intestinal epithelial immunological barrier function
- Functions via histone deacetylase inhibition
Medchemexpress LLC C18-ceramide | 2304-81-6 | 100.0% | 565.95 g/mol | C36H71NO3 | 25 MG
C18-ceramide is a saturated sphingolipid research reagent used to probe cellular signaling processes such as apoptosis, autophagy, endoplasmic reticulum stress, and PI3K/AKT pathway modulation. It is supplied as a high-purity powder for in vitro studies and should be stored under recommended conditions to preserve stability.
- High purity suitable for biochemical and cell-based assays
- Relevant for neuroscience and oncology research applications
- Modulates apoptosis, autophagy, and endoplasmic reticulum stress pathways
- Available in small, laboratory-friendly package sizes
- Stable when stored under recommended conditions for reproducible results